Hyaluronic acid promotes proliferation and migration of human meniscus cells via a CD44-dependent mechanism.

Tomohiko MurakamiShuhei OtsukiYoshinori OkamotoKosuke NakagawaHitoshi WakamaNobuhiro OkunoMasashi Neo

Published in: Connective tissue research (2018)

HA promoted human meniscus regeneration by inhibiting apoptosis, promoting cell migration, and accelerating cell proliferation, potentially through the PI3K/MAPK pathway via the CD44 receptor.

Keyphrases

hyaluronic acid
cell migration
endothelial cells
cell cycle arrest
cell proliferation
signaling pathway
induced apoptosis
oxidative stress
pi k akt
induced pluripotent stem cells
stem cells
endoplasmic reticulum stress
pluripotent stem cells