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Effectiveness and safety of CD22 and CD19 dual-targeting chimeric antigen receptor T-cell therapy in patients with relapsed or refractory B-cell malignancies: A meta-analysis.

Thi Thuy NguyenNguyen Thanh NhuChia-Ling ChenChiou-Feng Lin
Published in: Cancer medicine (2023)
Our meta-analysis demonstrated that the CD22/CD19 dual-targeting CAR-T-cell strategy has high efficiency with tolerable adverse effects in B-cell malignancies.
Keyphrases
  • high efficiency
  • systematic review
  • cancer therapy
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • diffuse large b cell lymphoma
  • meta analyses
  • multiple myeloma
  • drug delivery
  • randomized controlled trial