N6-methyladenosine-modified DBT alleviates lipid accumulation and inhibits tumor progression in clear cell renal cell carcinoma through the ANXA2/YAP axis-regulated Hippo pathway.

Daojia MiaoQi WangJian ShiQingyang LvDiaoyi TanChuanyi ZhaoZhiyong XiongXiaoping Zhang

Published in: Cancer communications (London, England) (2023)

This study demonstrated a tumor-suppressive role for the DBT/ANXA2/YAP axis-regulated Hippo signaling and suggested DBT as a potential target for pharmaceutical intervention in ccRCC.

Keyphrases

transcription factor
poor prognosis
mouse model
risk assessment