The modification of gelatin films: Based on various cross-linking mechanism of glutaraldehyde at acidic and alkaline conditions.

In order to investigate the effect of glutaraldehyde (GTA) on the structure, mechanical properties and thermal stability of gelatin films, gelatin films modified by GTA at various pH (4.5, 6.5, and 11), were prepared. According to FTIR analysis, the reaction mechanism between GTA and gelatin was different at various pH. With the addition of GTA, the intermolecular forces (hydrogen bonds and ionic bonds) and triple helix structure of gelatin film were significantly disrupted. At pH 4.5, gelatin films modified by GTA showed the highest mechanical properties and thermal stability among all films, which tensile strength and residues in TGA up to 16.13 MPa and 15.05%, respectively. Therefore, an optimum pH was around 4.5 in gelatin films cross-linked by GTA.