The effect of encomir-93 mimic transfection on the expression of miR-93 and PSA and androgen receptor in prostate cancer LNcap cell line.

Hossein MokhtariAli EbrahimiMohaddeseh NejatiZeinab BarartabarMehdi DamchiAbbas Khonakdar-Tarsi Mahlagha Zahedi

Published in: Hormone molecular biology and clinical investigation (2023)

The miR-93 and its target genes has important role in PCa progression via enhancement in PSA and AR expression. Further research on the function of the miR-93 and its target genes in tumorgenesis and progression PCa could be helpful for the treatment of prostate cancer.

Keyphrases

prostate cancer
long non coding rna
poor prognosis
cell proliferation
radical prostatectomy
long noncoding rna
genome wide
binding protein
bioinformatics analysis
dna methylation
gene expression
genome wide analysis
smoking cessation