Impacts of Pre-transplant Panel-Reactive Antibody on Post-transplantation Outcomes: A Study of Nationwide Heart Transplant Registry Data.
Darea KimJin Oh ChoiYang Hyun ChoKiick SungJaewon OhHyun-Jai ChoSung Ho JungHae-Young LeeJin Joo ParkYoungkeun AhnSeok-Min KangMyoung Soo KimJae-Joong KimPublished in: Korean circulation journal (2024)
Patients with cPRA ≥50% had significantly higher incidence of preformed DSA and lower freedom from AMR, but post-HTx survival rates were similar to those with cPRA <50%. Our findings suggest that sensitized patients can attain comparable post-transplant survival to non-sensitized patients when treated with optimal desensitization treatment and therapeutic intervention.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- randomized controlled trial
- prognostic factors
- heart failure
- peritoneal dialysis
- patient reported outcomes
- machine learning
- electronic health record
- artificial intelligence
- bone marrow
- insulin resistance
- smoking cessation
- antimicrobial resistance