Long Non-Coding RNA CAR10 Facilitates Non-Small Cell Lung Cancer Cell Migration and Invasion by Modulating the miR-892a/GJB2 Pathway.

Shanshan Li Yize Liu Guanzhen QiuYinzhou LuoLan LuanTiance XuYong WangShuyue Xia

Published in: Cancer management and research (2021)

CAR10 promoted NSCLC cell migration and invasion by upregulating GJB2 and sponging miR-892a. These findings illustrated that the CAR10/miR-892a/GJB2 axis may be a novel molecular target for the treatment of NSCLC.

Keyphrases

long non coding rna
poor prognosis
small cell lung cancer
cell proliferation
single cell
cell therapy
hearing loss
advanced non small cell lung cancer
long noncoding rna
bone marrow
mesenchymal stem cells
combination therapy
smoking cessation