Kinetic analysis of dominant intraprostatic lesion of prostate cancer using quantitative dynamic [18F]DCFPyL-PET: comparison to [18F]fluorocholine-PET.

Dae-Myoung YangFiona LiGlenn BaumanJoseph ChinStephen PautlerMadeleine MoussaIrina RachinskyJohn ValliantTing-Yim Lee

Published in: EJNMMI research (2021)

DIL was detected with good sensitivity and specificity using 22-min dynamic [18F]DCFPyL PET and avoids the need for delayed post-injection imaging timepoints. The dissimilar in vivo kinetic behaviour of [18F]DCFPyL and [18F]FCH could explain their different SUV images. Clinical Trial Registration NCT04009174 (ClinicalTrials.gov).

Keyphrases

pet ct
prostate cancer
clinical trial
positron emission tomography
high resolution
deep learning
computed tomography
convolutional neural network
open label
study protocol
phase ii
randomized controlled trial
ultrasound guided
clinical evaluation