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Multi-centre, three arm, randomized controlled trial on the use of methylprednisolone and unfractionated heparin in critically ill ventilated patients with pneumonia from SARS-CoV-2 infection: A structured summary of a study protocol for a randomised controlled trial.

Stefano BusaniMartina TosiPasquale MighaliPaola VandelliRoberto D'AmicoMarco MariettaFrancesco ForforiAbele DonatiGilda CinnellaAmato De MonteDaniela PaseroGiacomo BellaniCarlo TasciniGiuseppe FotiMarco RanieriMassimo Girardis
Published in: Trials (2020)
Protocol version 1.1 of April 26th, 2020. Recruitment start (expected): September 1st, 2020 Recruitment finish (expected): June 30th, 2021 TRIAL REGISTRATION: EudraCT number 2020-001921-30 , registered on April 15th, 2020 AIFA approval on May 4th, 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.
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