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Acetic Acid Enables Molecular Enumeration of Mycobacterium tuberculosis from Sputum and Eliminates the Need for a Biosafety Level 3 Laboratory.

Ana PalekyteAnna MorkowskaOwen BillingtonStephen Morris-JonesJames MillardMohlopheni J MarakalalaOlumuyiwa OwolabiBasil SambouAlimuddin ZumlaJayne S SutherlandTimothy D McHughIsobella Honeyborne
Published in: Clinical chemistry (2024)
READ-TB is an improved version of the MBLA and is available to be adopted by clinical microbiology laboratories as a tool for tuberculosis treatment monitoring. READ-TB will have a particular impact in low- and middle-income countries (LMICs) for laboratories with no BSL-3 laboratory and for clinical trials testing new combinations of anti-tuberculosis drugs.
Keyphrases
  • mycobacterium tuberculosis
  • pulmonary tuberculosis
  • clinical trial
  • single molecule
  • emergency department
  • randomized controlled trial
  • phase ii
  • hiv aids
  • hiv infected