Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemiology of COVID-19 disease.

Stephen W BicklerDavid M CauviKathleen M FischJames M PrietoAlicia G SykesHariharan ThangarajahDavid A LazarRomeo C IgnacioDale R GerstmannAllen F RyanPhilip E BicklerAntonio De Maio

Published in: BMC medical genomics (2021)

Assessment of PRR expression might provide a strategy for stratifying the risk of severe COVID-19 disease at both the individual and population levels.

Keyphrases

sars cov
coronavirus disease
poor prognosis
respiratory syndrome coronavirus
binding protein
long non coding rna
early onset
genome wide
gene expression
angiotensin ii