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Transcriptomic profiling of adipose tissue inflammation, remodeling, and lipid metabolism in periparturient dairy cows (Bos taurus).

David Salcedo-TacumaJair Parales-GironCrystal PromMiguel ChiriviJuliana LagunaAdam L LockGenaro Andres Contreras
Published in: BMC genomics (2020)
Results offer a comprehensive characterization of gene expression dynamics in periparturient AT, identify upstream regulators of AT function, and demonstrate complex interactions between lipid mobilization, inflammation, extracellular matrix remodeling, and redox signaling in the adipose organ.
Keyphrases
  • dairy cows
  • extracellular matrix
  • adipose tissue
  • gene expression
  • oxidative stress
  • single cell
  • insulin resistance
  • dna methylation
  • fatty acid
  • high fat diet
  • transcription factor
  • skeletal muscle
  • electron transfer