Effect of docosahexaenoic acid as an anti-inflammatory for Caco-2 cells and modulating agent for gut microbiota in children with obesity (the DAMOCLE study).

C LammiE OttavianoGiulia FioreC BollatiL d'AdduzioM FanzagaC CeccaraniS VizzusoG ZuccottiE BorghiE Verduci

Published in: Journal of endocrinological investigation (2024)

An improvement in gut dysbiosis of children with obesity seems to be triggered by DHA and to continue after discontinuation. The ability to modulate gut microbiota, matches also with an anti-inflammatory effect of DHA on Caco-2 cells.

Keyphrases

anti inflammatory
induced apoptosis
insulin resistance
metabolic syndrome
cell cycle arrest
weight loss
type diabetes
young adults
fatty acid
weight gain
high fat diet induced
endoplasmic reticulum stress
adipose tissue
cell death
body mass index