Cilostazol for secondary stroke prevention: systematic review and meta-analysis.

Choon Han TanAndrew Gr WuChing-Hui Sia Aloysius Sheng-Ting LeowBernard Pl ChanVijay Kumar Sharma Leonard Leong-Litt Yeo Benjamin Yong Qiang Tan

Published in: Stroke and vascular neurology (2021)

Cilostazol demonstrated superior efficacy and safety profiles compared with traditional antiplatelet regimens such as aspirin and clopidogrel for secondary stroke prevention but does not appear to affect functional outcomes. Future randomised trials can be conducted outside East Asia, or compare cilostazol with a wider range of antiplatelet agents.

Keyphrases

atrial fibrillation
antiplatelet therapy
clinical trial
acute coronary syndrome
low dose
percutaneous coronary intervention
open label
study protocol
double blind
cardiovascular events
randomized controlled trial
cerebral ischemia
type diabetes
placebo controlled
blood brain barrier
anti inflammatory drugs