Exercise training to increase tumour natural killer-cell infiltration in men with localised prostate cancer: a randomised controlled trial.

Sissal Sigmundsdóttir DjurhuusCasper SimonsenBirgitte Grønkaer ToftSimon Nørskov ThomsenSabrina WielsøeMartin Andreas RøderThomas HasselagerPeter Busch ØstergrenHenrik JakobsenBente Klarlund PedersenPernille HojmanKlaus BrassoJesper Frank Christensen

Published in: BJU international (2022)

Preoperative HIIT did not result in between-group differences in tumour NK-cell infiltration. Per-protocol and exploratory analyses demonstrate an enhanced NK-cell infiltration in PCa. Future studies are needed to test the capability of exercise to increase tumour immune cell infiltration.

Keyphrases

nk cells
prostate cancer
high intensity
randomized controlled trial
single cell
radical prostatectomy
stem cells
patients undergoing
cell therapy