OScc: an online survival analysis web server to evaluate the prognostic value of biomarkers in cervical cancer.
Qiang WangLu ZhangZhongyi YanLongxiang XieYang AnHuimin LiYali HanGuosen ZhangHuan DongHong ZhengWan ZhuYongqiang LiYunlong WangXiangqian GuoPublished in: Future oncology (London, England) (2019)
Aim: To establish a web server that can mutually validate prognostic biomarkers of cervical cancer. Methods: Four datasets including expression profiling and relative clinical follow-up data were collected from Gene Expression Omnibus and The Cancer Genome Atlas. The web server was developed by R software. Results: The web server was named OScc including 690 patients and can be accessed at http://bioinfo.henu.edu.cn/CESC/CESCList.jsp. The Kaplan-Meier survival curves with log-rank p-value and hazard ratio will be generated of interested gene in OScc. Compared with previous predictive tools, OScc had the advantages of registration-free, larger sample size and subgroup analysis. Conclusion: The OScc is highly valuable to perform the preliminary assessment and validation of new or interested prognostic biomarkers for cervical cancer.