Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug-Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil.

Published in: Clinical pharmacokinetics (2023)

These findings substantially enhance our comprehension of CYP2C8-mediated oxidation and DDIs, holding crucial implications for drug development and the planning of clinical trials involving these inhibitors.

Keyphrases

clinical trial
hydrogen peroxide
acute coronary syndrome
adverse drug
drug induced
randomized controlled trial
antiplatelet therapy
open label
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