Antifungal and antibacterial effects of newly created lactic acid bacteria associations depending on cultivation media and duration of cultivation.

The inhibitory effect of mixed LAB associations showed stronger dependence on the cultivation media and on the duration of cultivation with respect to each other. The co-cultivation of some strains, like L. rhamnosus MDC 9661, could lead to changed antagonistic activity. Consequently, the results are significant for creation and further investigation of LAB associations, as effective probiotics, and for their probable application in the production of antimicrobial preparations.