Azidomethylation of Nucleobases and Related N -Heterocycles, Benzazoles, and Bis(arene)sulfonimides Using Azidomethyl Esters with Silyl Triflates.

An efficient method for the azidomethylation of amines using azidomethyl esters with silyl triflates is described. This protocol enables the azidomethylation of various amines that can be activated with silyl groups, including nucleobases.