Whole-Genome Duplication Shapes the Aneuploidy Landscape of Human Cancers.

Kavya PrasadMathew Bloomfield Hagai Levi Kristina KeuperSara V BernhardNicolaas C BaudoinGil LeorYonatan EliezerMaybelline GiamCheng Kit WongGiulia RancatiZuzana Storchová Daniela Cimini Uri Ben-David

Published in: Cancer research (2022)

These findings suggest that the interactions between whole-genome duplication and aneuploidy are important for tumor evolution, highlighting the need to consider genome status in the analysis and modeling of cancer aneuploidy.

Keyphrases

endothelial cells
papillary thyroid
squamous cell
induced pluripotent stem cells
single cell
pluripotent stem cells
gene expression