Safety, Tolerability and Pharmacokinetics of Single Ascending and Multiple Oral Doses of Tegoprazan in Healthy Chinese Subjects.

Jinjie HeGuoying CaoJicheng YuJingjing WangNengneng ChengJufang WuWanzhen LiXiaojie WuBasheng ZhangJiayan LuShangzhi Chen

Published in: Clinical drug investigation (2020)

Tegoprazan was well tolerated in the dose range of 50-200 mg in single- and 100 mg in multiple-dose studies. Tegoprazan shows dose linearity with oral administration after a single dose of 50 to 200 mg and less drug accumulation after 10 days of continuous administration in 100 mg.

Keyphrases

randomized controlled trial
emergency department
pulmonary artery
adverse drug
placebo controlled
drug induced