A randomized crossover trial of regional anticoagulation modalities for intermittent hemodialysis.

Stanislas FaguerJean-Emmanuel SerreClara BrusqVanina BongardAudrey CasemayouOlivier MorannePierre PfirmannCédric RafatOlivier Cointault

Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)

In individuals at risk of bleeding, RA with calcium-free dialysate significantly reduces the incidence of premature dialysis termination compared to heparin-coated membrane without safety concerns. Trial registration and statistical analysis plan: ClinicalTrials.gov identifier: NCT03842657.

Keyphrases

peritoneal dialysis
end stage renal disease
phase iii
study protocol
chronic kidney disease
atrial fibrillation
venous thromboembolism
phase ii
clinical trial
open label
rheumatoid arthritis
risk factors
double blind
placebo controlled
randomized controlled trial
high intensity
disease activity
systemic sclerosis