The HDL mimetic CER-001 remodels plasma lipoproteins and reduces kidney lipid deposits in inherited lecithin:cholesterol acyltransferase deficiency.

Chiara PavanelloMarta TurriArianna StrazzellaPatrizia TulissiStefano PizzolittoGiovanna De MaglioRiccardo NappiLaura CalabresiGiuliano Boscutti

Published in: Journal of internal medicine (2021)

This study demonstrates that CER-001 may represent a therapeutic option in FLD patients. It also has the potential to be beneficial in other renal diseases characterized by kidney lipid deposits.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
fatty acid
peritoneal dialysis
prognostic factors
risk assessment
patient reported outcomes
human health
patient reported
replacement therapy