Opioid-free anesthesia versus opioid-based anesthesia in patients undergoing cardiovascular and thoracic surgery: a meta-analysis and systematic review.
Dave M MathewPeter J FuscoKathryn S VargheseAhmed K AwadEamon VegaSerena M MathewMia PolizziJerrin GeorgeChristopher S MathewJeremiah J ThomasRose CalixteAdham AhmedPublished in: Seminars in cardiothoracic and vascular anesthesia (2023)
Through the first pooled analysis of OBA vs OFA in a cardiothoracic-exclusive cohort, we found no significant difference in any of the pooled outcomes for thoracic surgery patients. Although limited to 2 cardiovascular surgery studies, OFA was associated with significantly reduced postoperative nausea and vomiting, inotrope need, and non-invasive ventilation in these patients. With growing use of OFA in invasive operations, further studies are needed to assess their efficacy and safety in cardiothoracic patients.
Keyphrases
- systematic review
- patients undergoing
- end stage renal disease
- thoracic surgery
- ejection fraction
- newly diagnosed
- chronic kidney disease
- chronic pain
- clinical trial
- metabolic syndrome
- minimally invasive
- peritoneal dialysis
- intensive care unit
- randomized controlled trial
- pain management
- weight loss
- coronary artery disease
- type diabetes
- skeletal muscle
- patient reported outcomes
- open label