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Posttransplant cyclophosphamide versus anti-thymocyte globulin versus combination for graft-versus-host disease prevention in haploidentical transplantation for adult acute myeloid leukemia: A report from the European Society for Blood and Marrow Transplantation Acute Leukemia Working Party.

Abdul-Hamid BazarbachiMyriam LabopinAnna Maria RaiolaDidier BlaiseWilliam ArceseStella SantaroneYener KocStefania BramantiAlexander KulaginMi KwonSimona SicaJaime SanzEolia BrissotArnon NaglerFabio CiceriMohamad Mohty
Published in: Cancer (2024)
The authors conclude that ATG alone is a less effective prophylaxis strategy compared to PTCy, however, the combination of PTCy and ATG is superior to either monotherapy. They propose that this combination could be considered a potential new standard of care for GVHD prophylaxis in haplo-SCT for AML.
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