Prognostic significance of PD-1 and PD-L1 positive tumor-infiltrating immune cells in ovarian carcinoma.

Paul BuderathFabian MairingerElena MairingerKatharina BöhmPawel MachKurt Werner SchmidRainer KimmigSabine Kasimir-BauerAgnes BankfalviDaniela WesterwickThomas Hager

Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2019)

Our results highlight the prognostic value of PD-1 and PD-L1 positive tumor-infiltrating immune cells in ovarian carcinoma. Their association with favorable prognosis supports the hypothesis that the expression of PD-1 and PD-L1 on tumor-infiltrating immune cells represents a strong immune response.

Keyphrases

immune response
poor prognosis
long non coding rna
toll like receptor
inflammatory response