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Aβ exacerbates α-synuclein-induced neurotoxicity through impaired insulin signaling in α-synuclein-overexpressed human SK-N-MC neuronal cells.

Ching-Chi ChangHsin-Hua LiYen-Ting ChangYing-Jui HoLing-Jia HsiehPai-Yi ChiuYu-Shih ChengChih-Li LinTe-Jen Lai
Published in: CNS neuroscience & therapeutics (2017)
This raised the possibility that insulin resistance could be one of the causative factors of αSyn toxicity, and the strategies for insulin sensitization may have therapeutic potential for synucleinopathies including DLB.
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