High-intensity interval training improves inflammatory and adipokine profiles in postmenopausal women with metabolic syndrome.
Flávia Mariel StecklingJuliano Boufleur FarinhaFelipe da Cunha FigueiredoDaniela Lopes Dos SantosGuilherme BrescianiNélson Alexandre KretzmannSílvio Terra StefanelloAline Alves CourtesMaristela de Oliveira BeckManuela Sangoi CardosoMarta Maria Medeiros Frescura DuarteRafael Noal MorescoFelix Alexandre Antunes SoaresPublished in: Archives of physiology and biochemistry (2018)
This study investigate the effects of high-intensity interval training (HIIT) on systemic levels of inflammatory and hormonal markers in postmenopausal women with metabolic syndrome (MS). Fifteen postmenopausal women with MS completed the training on treadmills. Functional, body composition parameters, maximal oxygen uptake (VO2max), and lipid profile were assessed before and after HIIT. Serum or plasma levels of cytokines and hormonal markers were measured along the intervention. The analysis of messenger RNA (mRNA) expression of these cytokines was performed in peripheral blood mononuclear cells (PBMC). VO2max and some anthropometric parameters were improved after HIIT, while decreased levels of proinflammatory markers and increased levels of interleukin-10 (IL-10) were also found. Adipokines were also modulated after 12 weeks or training. The mRNA expression of the studied genes was unchanged after HIIT. In conclusion, HIIT benefits inflammatory and hormonal axis on serum or plasma samples, without changes on PBMC of postmenopausal MS patients.
Keyphrases
- body composition
- bone mineral density
- high intensity
- metabolic syndrome
- resistance training
- mass spectrometry
- multiple sclerosis
- virtual reality
- ms ms
- postmenopausal women
- oxidative stress
- end stage renal disease
- polycystic ovary syndrome
- randomized controlled trial
- insulin resistance
- ejection fraction
- newly diagnosed
- breast cancer risk
- uric acid
- peritoneal dialysis
- skeletal muscle
- heart rate
- prognostic factors
- gene expression
- drug induced