Sex-specific associations of human milk long-chain polyunsaturated fatty acids and infant allergic conditions.

Kozeta MilikuJacqueline RichelleAllan B BeckerElinor SimonsTheo J MoraesTurvey E StuartPiush J MandhaneMalcolm R SearsPadmaja SubbaraoCatherine J FieldMeghan B Azad

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2021)

Human milk PUFA proportions and their ratios are associated with infant atopic conditions in a sex-specific manner. In female infants, a higher ratio of ARA/DHA may reduce the risk of food sensitization and atopic dermatitis. Further research is needed to determine the underlying mechanisms and clinical relevance of this sex-specific association.

Keyphrases

human milk
atopic dermatitis
low birth weight
preterm infants
preterm birth
fatty acid
climate change
human health
allergic rhinitis