Three molecules found in rosemary or nutmeg essential oils repel ticks (Dermacentor variabilis) more effectively than DEET in a no-human assay.

Our assay focused on comparing active ingredients as potential repellents and found that many natural products can elicit a strong response from ticks. Terpinolene is the most promising active ingredient identified, owing to human health concerns regarding myristicin and safrole. Our results from examining individual terpenoids from two essential oils suggest that there remain unexploited natural compounds that could be further developed for new personal tick repellents. © 2020 Society of Chemical Industry.