Longitudinal Evaluation of Aortic Hemodynamics in Marfan Syndrome: New Insights from a 4D Flow Cardiovascular Magnetic Resonance Multi-Year Follow-Up Study.
Julia GeigerDaniel HirtlerKristina GottfriedOzair RahmanEmilie BollacheAlex J BarkerMichael MarklBrigitte StillerPublished in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2017)
MFS patients have lower segmental WSS in the inner proximal DAo segment which correlates with increased localized aberrant vortex/helix flow patterns and an enlarged diameter at one of the most critical sites for aortic dissection. General aortic hemodynamics are stable but these subtle localized DAo changes are already present at young age and tend to be more pronounced in the course of time.
Keyphrases
- aortic dissection
- magnetic resonance
- end stage renal disease
- aortic valve
- newly diagnosed
- chronic kidney disease
- ejection fraction
- peritoneal dialysis
- left ventricular
- heart failure
- prognostic factors
- pulmonary artery
- cross sectional
- transcription factor
- coronary artery
- patient reported
- middle aged
- dna binding
- pulmonary arterial hypertension
- optic nerve