Low level of stromal lectin-like oxidized LDL receptor 1 and CD8+ cytotoxic T-lymphocytes indicate poor prognosis of colorectal cancer.

Chika Katayama Takehiko YokoboriNaoya OzawaKunihiko SugaTakuya ShiraishiTakuhisa OkadaKatsuya OsoneRyuji KatohToshinaga SutoYoko MotegiHiroomi OgawaAkihiko SanoMakoto SakaiMakoto SohdaBilguun Erkhem-OchirNavchaa GombodorjAyaka KatayamaTetsunari OyamaKen ShirabeHiroyuki KuwanoHiroshi Saeki

Published in: Cancer reports (Hoboken, N.J.) (2021)

The MDSC marker, LOX-1, was mainly expressed by M2 macrophages in CRC tissues. LOX-1+ macrophages and CD8+ CTLs may serve as useful biomarkers for predicting the prognosis of CRC.

Keyphrases

poor prognosis
low density lipoprotein
long non coding rna
gene expression
bone marrow
nk cells