Efficacy of Allopurinol in Improving Endothelial Dysfunction: A Systematic Review and Meta-Analysis.

Shurjeel Uddin QaziUsama QamarMuhammad Talha MaqsoodRabbia GulSaad Ali AnsariZeeshan ImtiazAmatul NoorMohammed Zia Khan SuhebZaofashan ZaheerAdeela AndleebMasooma NaseemMuhammad Shariq AkramMubarak AliAlina BarmanwallaRutab TareenIrfa Zaheer

Published in: High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension (2023)

While allopurinol may improve endothelial function in various patient populations, further high-quality randomized controlled trials are needed to determine its efficacy in preventing cardiovascular disease exacerbation.

Keyphrases

cardiovascular disease
randomized controlled trial
type diabetes
case report
systematic review
clinical trial
metabolic syndrome
intensive care unit
coronary artery disease
cardiovascular risk factors
study protocol
genetic diversity
extracorporeal membrane oxygenation