Prognostic value of natural killer cell/T cell ratios for disease activity in multiple sclerosis.
Max MimpenAnne-Hilde MurisLinda RolfOliver GerlachJens KuhleRaymond HuppertsJoost J F M SmoldersJan DamoiseauxPublished in: European journal of neurology (2020)
Our data suggest a protective role of an expanded NK cell compartment compared to the CD4+ T cell subset fractions in relapsing-remitting MS patients. NK/CD4+ T cell ratios may be a prognostic biomarker for disease activity in MS.
Keyphrases
- disease activity
- multiple sclerosis
- systemic lupus erythematosus
- rheumatoid arthritis
- nk cells
- rheumatoid arthritis patients
- ankylosing spondylitis
- juvenile idiopathic arthritis
- end stage renal disease
- mass spectrometry
- chronic kidney disease
- white matter
- ms ms
- newly diagnosed
- ejection fraction
- prognostic factors
- electronic health record
- peritoneal dialysis
- single cell
- cell therapy
- patient reported outcomes
- machine learning