Exosomes Secreted During Myogenic Differentiation of Human Fetal Cartilage-Derived Progenitor Cells Promote Skeletal Muscle Regeneration through miR-145-5p.
Dong Il ShinYong Jun JinSujin NohHee-Woong YunDo Young ParkByoung-Hyun MinPublished in: Tissue engineering and regenerative medicine (2024)
F-Exo improved muscle regeneration by activating the Wnt signaling pathway via abundant miR-145-5p, mimicking the remarkable myogenic differentiation potential of hFCPCs.
Keyphrases
- skeletal muscle
- stem cells
- signaling pathway
- insulin resistance
- endothelial cells
- pi k akt
- mesenchymal stem cells
- epithelial mesenchymal transition
- cell proliferation
- induced pluripotent stem cells
- induced apoptosis
- extracellular matrix
- wound healing
- pluripotent stem cells
- risk assessment
- adipose tissue
- oxidative stress
- metabolic syndrome
- bone marrow