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Administration of 4% tetrasodium EDTA lock solution and central venous catheter complications in high-risk pediatric patients with intestinal failure: A retrospective cohort study.

Thomas I HirschScott C FligorSavas T TsikisPaul D MitchellAngela DeVietroSarah CarbeauSarah Ziqi WangJennifer McClellandAlexandra N CareyKathleen M GuraMark Puder
Published in: JPEN. Journal of parenteral and enteral nutrition (2024)
In a compassionate use protocol for high-risk pediatric patients with intestinal failure, the use of 4% T-EDTA reduced composite catheter complications, including those leading to emergency department visits, hospital admissions, additional procedures, and mortality. This outcome suggests 4% T-EDTA has benefits over currently available lock solutions.
Keyphrases
  • emergency department
  • risk factors
  • randomized controlled trial
  • cardiovascular events
  • type diabetes
  • cardiovascular disease
  • childhood cancer