Administration of 4% tetrasodium EDTA lock solution and central venous catheter complications in high-risk pediatric patients with intestinal failure: A retrospective cohort study.
Thomas I HirschScott C FligorSavas T TsikisPaul D MitchellAngela DeVietroSarah CarbeauSarah Ziqi WangJennifer McClellandAlexandra N CareyKathleen M GuraMark PuderPublished in: JPEN. Journal of parenteral and enteral nutrition (2024)
In a compassionate use protocol for high-risk pediatric patients with intestinal failure, the use of 4% T-EDTA reduced composite catheter complications, including those leading to emergency department visits, hospital admissions, additional procedures, and mortality. This outcome suggests 4% T-EDTA has benefits over currently available lock solutions.