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History of Cardiovascular Disease, Intensive Lifestyle Intervention, and Cardiovascular Outcomes in the Look AHEAD Trial.

null nullCora Elizabeth LewisJohn P BantleAlain G BertoniGeorge BlackburnFrederick L BrancatiGeorge A BrayLawrence J CheskinJeffrey M CurtisCaitlin EganMary EvansJohn P ForeytSiran GhazarianBethany Barone GibbsStephen P GlasserEdward W GreggHelen P HazudaLouise HessonJames O HillEdward S HortonVan S HubbardJohn Michael JakicicRobert W JefferyKaren C JohnsonSteven E KahnAbbas E KitabchiDalane KitzmanWilliam C KnowlerEdward LipkinSara MichaelsMaria G MontezDavid M NathanEbenezer NyenweJennifer PatricioAnne PetersXavier Pi-SunyerHenry PownallDavid M ReboussinDonna H RyanThomas A WaddenLynne E WagenknechtHolly WyattRena R WingSusan Z Yanovski
Published in: Obesity (Silver Spring, Md.) (2020)
Intervention response heterogeneity was significant for nonfatal MI. Response heterogeneity may need consideration in a CVD-outcome trial design.
Keyphrases
  • cardiovascular disease
  • randomized controlled trial
  • study protocol
  • phase iii
  • single cell
  • clinical trial
  • metabolic syndrome
  • type diabetes
  • physical activity
  • weight loss