Long non-coding RNA CASC8 polymorphisms are associated with the risk of esophageal cancer in a Chinese population.

CASC8 rs1562430 A > G may cause susceptibility to ESCC and CASC8 SNPs may play a vital role in ESCC risk, thereby serving as a potential biomarker for diagnosing ESCC. A larger sample size and multifactor information are needed to confirm these results.