Association Between Frailty and Antiseizure Medication Tolerability in Older Adults With Epilepsy.

Arielle Vary-O'NealSareh MiranzadehNafisa HuseinJayna M Holroyd-Leduc Tolulope T Sajobi Samuel WiebeCharles DeaconJose Francisco Tellez-Zenteno Colin Bruce Josephson Mark R Keezer

Published in: Neurology (2022)

The EFS was significantly, both statistically and clinically, associated with ASM tolerability. It also showed multiple advantages in performance while assessing for frailty in older adults with epilepsy, as compared to the two other measures of frailty that we tested. Future studies must focus on what role the EFS at the time of epilepsy diagnosis may play in ASM selection among older adults with epilepsy.

Keyphrases

community dwelling
open label
physical activity
middle aged
healthcare
randomized controlled trial
emergency department
study protocol