Quantifying the impact of immunotherapy on RNA dynamics in cancer.
Ieva UsaiteDhruva BiswasKrijn DijkstraThomas Bk WatkinsOriol PichClare PuttickMihaela AngelovaKrupa ThakkarCrispin HileyNicolai Juul BirkbakMarleen KokSimone ZaccariaYin WuKevin LitchfieldCharles SwantonNnennaya KanuPublished in: Journal for immunotherapy of cancer (2023)
Overall, delineating longitudinal RNA dynamics following CPI therapy sheds light on the mechanisms underlying diverging response trajectories, and identifies putative targets for combination therapy.