Myeloid spatial and transcriptional molecular signature of ischemia-reperfusion injury in human liver transplantation.

Rebecca A SosaRichard AhnFang LiAllyson Q TerryZach QianAdil BhatSubha SenBita V NainiTakahiro ItoFady M KaldasRebecca A SosaRonald W BusuttilJerzy W Kupiec-WeglinskiDavid W GjertsonElaine F Reed

Published in: Hepatology communications (2024)

Myeloid subset-specific genes and related signaling pathways provide targets for the development of therapeutic strategies aimed at limiting IRI in the clinical setting of liver transplantation.

Keyphrases

dendritic cells
bone marrow
endothelial cells
acute myeloid leukemia
signaling pathway
induced pluripotent stem cells
genome wide
gene expression
transcription factor
pluripotent stem cells
pi k akt
genome wide identification
dna methylation
genome wide analysis