Effectiveness of Ultraviolet-C Disinfection on Hospital-Onset Gram-Negative Rod Bloodstream Infection: A Nationwide Stepped-Wedge Time-Series Analysis.

Michihiko GotoShinya HasegawaErin C BalkenendeGosia S CloreNasia SafdarEli N Perencevich

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

In this large quasi-experimental analysis within the VHA System, enhanced terminal room cleaning with UV-C disinfection was associated with an approximately 19% lower incidence of HO-GNR BSI, with wide variability in effectiveness among hospitals. Further studies are needed to identify the optimal implementation strategy to maximize the effectiveness of UV-C disinfection technology.

Keyphrases

gram negative
drinking water
randomized controlled trial
systematic review
multidrug resistant
healthcare
primary care
risk factors
emergency department
clinical trial
klebsiella pneumoniae