How We Manage Bone Marrow Edema-An Interdisciplinary Approach.
Sebastian Felix BaumbachVanessa PfahlerSusanne Bechtold-Dalla PozzaIsa Feist-PagenstertJulian FürmetzAndrea Baur-MelnykUlla Cordula StumpfMaximilian Michael SallerAndreas StraubeRalf SchmidmaierJan LeipePublished in: Journal of clinical medicine (2020)
Bone marrow edema (BME) is a descriptive term for a common finding in magnetic resonance imaging (MRI). Although pain is the major symptom, BME differs in terms of its causal mechanisms, underlying disease, as well as treatment and prognosis. This complexity together with the lack of evidence-based guidelines, frequently makes the identification of underlying conditions and its management a major challenge. Unnecessary multiple consultations and delays in diagnosis as well as therapy indicate a need for interdisciplinary clinical recommendations. Therefore, an interdisciplinary task force was set up within our large osteology center consisting of specialists from internal medicine, endocrinology/diabetology, hematology/oncology, orthopedics, pediatrics, physical medicine, radiology, rheumatology, and trauma surgery to develop a consenus paper. After review of literature, review of practical experiences (expert opinion), and determination of consensus findings, an overview and an algorithm were developed with concise summaries of relevant aspects of the respective underlying disease including diagnostic measures, clinical features, differential diagnosis and treatment of BME. Together, our single-center consensus review on the management of BME may help improve the quality of care for these patients.
Keyphrases
- bone marrow
- magnetic resonance imaging
- clinical practice
- mesenchymal stem cells
- end stage renal disease
- palliative care
- contrast enhanced
- healthcare
- newly diagnosed
- mental health
- ejection fraction
- pain management
- chronic pain
- computed tomography
- machine learning
- chronic kidney disease
- quality improvement
- minimally invasive
- case report
- artificial intelligence
- preterm infants
- magnetic resonance
- deep learning
- cross sectional
- coronary artery bypass
- general practice
- patient reported outcomes
- stem cells
- patient reported
- rheumatoid arthritis
- juvenile idiopathic arthritis
- molecularly imprinted
- gestational age
- simultaneous determination
- bioinformatics analysis