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Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease.

Jake GockleyKelsey S MontgomeryWilliam L PoehlmanJesse C WileyYue LiuEkaterina GerasimovAnna K GreenwoodSolveig K SiebertsAliza P WingoThomas S WingoLara M MangraviteBenjamin A Logsdon
Published in: Genome medicine (2021)
We provide evidence of cis-genetic variation conferring AD risk through 8 genes across six distinct genomic loci. Moreover, we provide expression weights for 6780 genes as a valuable resource to the community, which can be abstracted across the neocortex and a wide range of neuronal phenotypes.
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