A randomized, double-blind, placebo-controlled pilot trial of low-intensity pulsed ultrasound therapy for refractory angina pectoris.
Tomohiko ShindoKenta ItoTsuyoshi OgataRyo KurosawaKumiko EguchiYuta KagayaKenichiro HanawaYuhi HasebeKensuke NishimiyaTakashi ShirotoJun TakahashiYasuo OkumuraTeruo NoguchiYukio OzakiHiroyuki DaidaNobuhisa HagiwaraTohru MasuyamaTaishiro ChikamoriYoshihiro FukumotoKenichi TsujitaHiroshi KanaiSatoshi YasudaHiroaki ShimokawaPublished in: PloS one (2023)
In the present study, the LIPUS therapy did not further ameliorate chest pain as compared with optimal medications alone in patients with refractory angina pectoris. The present findings need to be confirmed in another trial with a large number of patients. (Registration ID: UMIN000012369).
Keyphrases
- placebo controlled
- double blind
- phase iii
- end stage renal disease
- clinical trial
- study protocol
- coronary artery disease
- phase ii
- coronary artery
- ejection fraction
- newly diagnosed
- chronic kidney disease
- percutaneous coronary intervention
- randomized controlled trial
- computed tomography
- peritoneal dialysis
- patient reported outcomes
- radiation therapy
- squamous cell carcinoma
- atrial fibrillation
- open label
- bone marrow
- phase ii study
- contrast enhanced ultrasound
- mesenchymal stem cells