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Computational identification of clonal cells in single-cell CRISPR screens.

Yihan WangShiqi XieDaniel ArmendarizGary C Hon
Published in: BMC genomics (2022)
Experimental conditions that reduce clonal expansion or computational filtering of clonal cells will improve the reliability of single-cell CRISPR screens.
Keyphrases
  • single cell
  • genome wide
  • induced apoptosis
  • high throughput
  • cell cycle arrest
  • rna seq
  • crispr cas
  • genome editing
  • dna methylation
  • endoplasmic reticulum stress
  • pi k akt