Serum iron levels in tuberculosis patients and household contacts and its association with natural resistance-associated macrophage protein 1 polymorphism and expression.
Wiendra WaworuntuFrancisca Srioetami TanoerahardjoAnwar MallongiAhyar AhmadMuhammad AminIrawaty DjaharuddinAgussalim BukhariNur Ahmad TabriBurhanuddin BaharNajdah -HidayahHandayani HalikMuhammad Nasrum MassiPublished in: The clinical respiratory journal (2023)
Comparing the TB case to the household contacts group, decreased serum Fe levels were discovered in the TB case group. This study also shows a correlation of NRAMP1 gene expression to Fe levels in TB patients and household contacts and describes that TB may lead to decreased Fe levels by downregulating NRAMP1 expression.
Keyphrases
- mycobacterium tuberculosis
- end stage renal disease
- gene expression
- poor prognosis
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- emergency department
- binding protein
- long non coding rna
- small molecule
- metal organic framework
- protein protein
- aqueous solution
- antiretroviral therapy
- iron deficiency