ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban.

An-Jing RenChun-Chun Wei Ya-Jin LiuMengna LiuPing Wang Juan FanKai WangSha ZhangZhenbang QinQiu-Xiao RenYanjun ZhengYu-Xia Chen Zhifang XieLing GaoYi Zhu Youyi Zhang Huang-Tian Yang Weiping J Zhang

Published in: Circulation research (2024)

These data point to ZBTB20 as a fine-tuning modulator of PLN expression and SERCA2a activity, thereby offering new perspective on the regulation of basal contractility in the mammalian heart.

Keyphrases

poor prognosis
smooth muscle
heart failure
left ventricular
electronic health record
atrial fibrillation
machine learning