Exosomal miR-17-3p Alleviates Programmed Necrosis in Cardiac Ischemia/Reperfusion Injury by Regulating TIMP3 Expression.

Zhuyuan LiuDidi ZhuFuchao YuMingming YangDan HuangZhenjun JiWenbin LuGenshan Ma

Published in: Oxidative medicine and cellular longevity (2022)

The present study demonstrated that exosomal miR-17-3p alleviated the programmed necrosis associated with cardiac I/R injury by regulating TIMP3 expression. These findings could represent a potential treatment for I/R injury.

Keyphrases

poor prognosis
ischemia reperfusion injury
left ventricular
oxidative stress
binding protein
long non coding rna
atrial fibrillation
human health