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Overinterpretation is common in pathological diagnosis of appendix cancer during patient referral for oncologic care.

Mark A ValasekIrene ThungEsha GollapalleAlexey A HodkoffKaitlyn J KellyJoel M BaumgartnerVera VavinskayaGrace Y LinAnn P TippsMojgan V HosseiniAndrew M Lowy
Published in: PloS one (2017)
Appendiceal mucinous lesions remain a difficult area for appropriate pathological classification with substantial discordance due to over-interpretation in this study. The findings highlight the critical need for recognition and application of diagnostic criteria regarding these tumors. Recently published consensus guidelines and a checklist provided herein may help facilitate improvement of diagnostic concordance and thereby reduce over-interpretation and potential overtreatment. Further studies are needed to determine the extent of this phenomenon and its potential clinical impact.
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